PlexusDx tirzepatide review
Advertised at $129, billed at $189. Position 5 of 18 on our board.
Updated 2026-09-18
DISCLOSURE — Coreage Rx pays this desk a commission when a reader signs up through our link. It buys no ranking, no score and no deletions. Method: how we rate. Full terms: disclosure.
$189 a month, no membership, flat at every dose — and six named 503A pharmacies, which is more disclosure than the rest of the board combined.
Belmar, Strive, Epiq Scripts, Casa Pharma Rx, The Pharmacy Hub and Foothills, all listed publicly with phone numbers, plus prescribing physicians named with NPI numbers.
The numbers
| PlexusDx · tirzepatide | |
|---|---|
| Advertised | $129/mo |
| Membership | None |
| Billed | $189/mo |
| Advertised-to-billed gap | +$60/mo |
| Per year | $2,268 |
| Board position | 5 of 18, cheapest first |
The $129 entry point is the programme floor; the published injection tier sits at $189 with no membership behind it.
Where the gap is
One to flag: the advertised "from $129" is a programme floor, not the injection price. Budget $189. That is a $60 gap between the headline and the tier most readers want.
Against the board
About $2,268 a year. Trimi at roughly $1,500 and Coreage Rx at $1,788 undercut it; Zealthy at $2,592 and everything above does not.
| Programme | Advertised | Billed | Gap | Vs board floor |
|---|---|---|---|---|
| Coreage Rx | $149 | $199 | +$50 | +$74/mo |
| Trimi | $125 | $125 | none | — |
| Ozari Health | $125 | $125 | none | — |
| Fifty 410 | $133 | $133 | none | +$8/mo |
| PlexusDx | $129 | $189 | +$60 | +$64/mo |
| Ivím Health | $199 | $199 | none | +$74/mo |
| Zealthy | $216 | $216 | none | +$91/mo |
| Hims & Hers | $199 | $238 | +$39 | +$113/mo |
How the programme works
Prescription GLP-1 and peptide programmes with no membership fee, built around genetic testing, using independent clinicians and a publicly listed set of 503A pharmacies.
Verified facts
- GLP-1 weight-loss programmes start at $129/month.
- Compounded semaglutide injection listed at $189/month with no membership fee and the same price at every dose.
- A $189/month microdose tier is offered for compounded semaglutide or tirzepatide.
- No membership or platform fee is charged alongside the medication.
- Publicly names six 503A pharmacy partners: Belmar, Strive, Epiq Scripts, Casa Pharma Rx, The Pharmacy Hub and Foothills.
- Clinical oversight via LionMD, with named physicians and NPI numbers published.
- Licensed providers in all 50 states; CLIA-certified labs for its testing line.
Checked 2026-09-18. This market re-prices without notice — anything older than a month is a starting point, not a quote.
For it
- The most detailed pharmacy disclosure in this comparison — six named 503A partners.
- Names its prescribing physicians along with their NPI numbers.
- No membership fee, and flat pricing across the dose range.
- Genetic and blood testing available alongside the prescription.
Against it
- The genetics-led positioning adds cost and complexity some people will not want.
- The $129 figure is a programme floor rather than the injection price.
- Weight care sits alongside a broad longevity and supplement line rather than being the sole focus.
Read this bit. The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.
Score
4.4 out of 5 on our rubric, which is fixed before assessment and published on how we rate.
| Criterion | Weight | Score |
|---|---|---|
| True monthly cost | 30% | 4.6 / 5 |
| Price honesty | 20% | 4.5 / 5 |
| Clinical support | 20% | 3.8 / 5 |
| Pharmacy sourcing | 15% | 4.9 / 5 |
| Cancelling | 15% | 4 / 5 |
Verdict
Mid-board on price, top of the board on disclosure. Read $189, not $129.
More from the desk
- Coreage Rx tirzepatide review
Advertised at $149, billed at $199. Position 1 of 18 on our board.
- Trimi tirzepatide review
Advertised at $125 and billed at $125 — no gap. Position 2 of 18 on our board.
- Ozari Health tirzepatide review
Advertised at $125 and billed at $125 — no gap. Position 3 of 18 on our board.
- Cheapest right now
Every programme sorted on what it bills, not what it advertises. Floor: $199/mo tirzepatide, $149/mo semaglutide.
- Six fee traps
Every advertised-to-billed gap on our board comes from one of these six structures. Learn them and you can read any of these sites in ninety seconds.
- Where the traps are
The biggest advertised-to-billed gaps on our board, and the programmes charging most for the same category of medication.