Noom Med vs PlexusDx

Both sell tirzepatide. Noom Med costs $149 a month and PlexusDx costs $189, a difference of $40 a month or about $480 a year. The desk reads it as follows.

Noom Med is behaviour change alongside medication. PlexusDx is pharmacy transparency and genetic testing. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though on this board it usually is.

Advert against bill. Noom Med advertises $149 and bills $149; PlexusDx advertises $129 and bills $189. The gaps are different sizes, which means comparing the two on their advertised prices gives you the wrong answer.

Side by side

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

The split

They differ on 4 of the 7 things we track, and behave the same on the other 3. The differences are what the price gap is actually buying.

What each puts on the record: Noom Med

• Noom Med listed from $149/month.
• Microdose GLP-1Rx programme listed from $79/month with medication included.
• Programme pairs low-dose medication with biomarker monitoring and coaching.

Where it wins: The coaching is the actual product here and it is well built. Watch for: A $79 microdose programme is not the same treatment as 10 mg tirzepatide. Check the dose before comparing on price.

What each puts on the record: PlexusDx

• GLP-1 weight-loss programmes start at $129/month.
• Compounded semaglutide injection listed at $189/month with no membership fee and the same price at every dose.
• A $189/month microdose tier is offered for compounded semaglutide or tirzepatide.
• No membership or platform fee is charged alongside the medication.
• Publicly names six 503A pharmacy partners: Belmar, Strive, Epiq Scripts, Casa Pharma Rx, The Pharmacy Hub and Foothills.
• Clinical oversight via LionMD, with named physicians and NPI numbers published.
• Licensed providers in all 50 states; CLIA-certified labs for its testing line.

Where it wins: The most detailed pharmacy disclosure in this comparison — six named 503A partners. Watch for: The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.

In each one’s favour

Noom Med.

• The coaching is the actual product here and it is well built.
• Medication is included in the microdose tier rather than billed separately.

PlexusDx.

• The most detailed pharmacy disclosure in this comparison — six named 503A partners.
• Names its prescribing physicians along with their NPI numbers.

How they score

PlexusDx scores higher overall at 4.4 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

The desk’s call

• Pick Noom Med if cost is the binding constraint. Over a year the gap is about $480, which is real money for the same class of medication.
• Pick PlexusDx if what it does better matters to you — the most detailed pharmacy disclosure in this comparison — six named 503a partners.
• If sourcing matters, note that PlexusDx publishes which pharmacy compounds its medication and Noom Med does not.

The verdict

On the board, Noom Med at $149 a month is the more defensible choice on arithmetic alone. PlexusDx earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Noom Med and PlexusDx.

How they sit against everyone else