Rankings

The best GLP-1 programmes

Every provider we track, scored on the same five weighted criteria, whichever medication they dispense.

Updated 2026-09-18

DISCLOSURE — Coreage Rx pays this desk a commission when a reader signs up through our link. It buys no ranking, no score and no deletions. Method: how we rate. Full terms: disclosure.

One table, every provider, the same rubric applied to all of them — compounded and branded, cheap and expensive.

Because the rubric weights true monthly cost most heavily, the cheap end does well here. But price honesty, clinical support, pharmacy sourcing and cancellation terms all count, which is why the very cheapest option is not automatically top.

What gets a listing on this board

Every provider offering tirzepatide, compounded or branded.
Scored on the published weighted rubric.
No minimum price or feature requirement — this is the full field.

21 of the 21 providers we track qualify. Board verified 2026-09-18 and re-checked periodically.

The list

#	Provider	Per month	Per year	Score
1	Coreage Rx	$199	$2,388	4.5
2	Trimi	$125	$1,500	4.6
3	PlexusDx	$189	$2,268	4.4
4	Ozari Health	$125	$1,500	4.4
5	Fifty 410	$133	$1,596	4.2
6	Ivím Health	$199	$2,388	4
7	Mochi Health	$278	$3,336	3.6
8	Coby Health	$239	$2,868	3.6
9	Hims & Hers	$238	$2,856	3.5
10	Ro	$448	$5,376	3.5
11	Zealthy	$216	$2,592	3.5
12	LifeMD	$149	$1,788	3.5
13	Noom Med	$149	$1,788	3.5
14	Remedy Meds	$399	$4,788	3.5
15	Lemonaid Health	$348	$4,176	3.5
16	WeightWatchers Clinic	$74	$888	3.2
17	Eden	$298	$3,576	3.1
18	Henry Meds	$449	$5,388	3
19	TrimRx	$399	$4,788	2.9
20	Willow	$399	$4,788	2.9
21	MEDVi	$399	$4,788	2.8

Cheapest qualifying option: WeightWatchers Clinic at $74 a month. Our featured partner is pinned to the top of the list where it qualifies — see how we rate for who scores higher.

1. Coreage Rx — Best overall on true monthly cost

$199 a month, no membership fee. Flat-rate telehealth program for compounded GLP-1s. The medication, the clinician visits and the ongoing check-ins are quoted as one number, with no separate membership billed alongside it.

The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Read the full Coreage Rx review.

2. Trimi — Lowest flat price with named pharmacies

$125 a month, no membership fee. Flat-rate compounded GLP-1 programme on annual plans, with medical oversight through the Arora Health clinician network and publicly named 503A compounding pharmacies.

Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Read the full Trimi review.

3. PlexusDx — Pharmacy transparency and genetic testing

$189 a month, no membership fee. Prescription GLP-1 and peptide programmes with no membership fee, built around genetic testing, using independent clinicians and a publicly listed set of 503A pharmacies.

The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Read the full PlexusDx review.

Reader questions

How do you score these?

True monthly cost 30%, price honesty 20%, clinical support 20%, pharmacy sourcing 15%, cancellation 15%. Weights are fixed before assessment and published in full.

How often is this updated?

Pricing is re-verified periodically and every review carries the date it was last checked. This market re-prices without notice.

Caveat from the desk

Compounded preparations are not FDA-approved. Two approved oral GLP-1s now start around $149 a month, and from 1 July 2026 eligible Medicare beneficiaries can access certain GLP-1s for $50 a month — both of which beat a large part of this market. See the approved pills and the Medicare programme.

In SURMOUNT-1, adults with obesity lost an average of 19.5% of body weight on 10 mg and 20.9% on 15 mg over 72 weeks. That figure comes from a controlled trial of the active ingredient, not from any particular seller's product.