Trimi vs Fifty 410

Both sell tirzepatide. Trimi costs $125 a month and Fifty 410 costs $133, a difference of $8 a month or about $96 a year. The desk reads it as follows.

Trimi is lowest flat price with named pharmacies. Fifty 410 is prepaid blocks with no subscription. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though on this board it usually is.

Side by side

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

Where Trimi wins

• The cheapest verified flat rate for compounded tirzepatide in this comparison.
• Names its pharmacies with a licence number and offers a certificate of analysis — almost nobody else in this market does.
• Price does not move as your dose is adjusted.
• No membership fee stacked on the medication price.

Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months.

Where Fifty 410 wins

• Genuinely no subscription — you buy a block and nothing recurs.
• Among the lowest tirzepatide rates verified.
• Unusually detailed public explanation of 503A standards and batch testing.
• No payment taken until a provider approves you.

The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments.

How they score

Trimi scores higher overall at 4.6 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which should you pick?

• Pick Trimi if cost is the binding constraint. Over a year the gap is about $96, which is real money for the same class of medication.
• Pick Fifty 410 if what it does better matters to you — genuinely no subscription — you buy a block and nothing recurs.
• If sourcing matters, note that Trimi publishes which pharmacy compounds its medication and Fifty 410 does not.

The verdict

On the board, Trimi at $125 a month is the more defensible choice on arithmetic alone. Fifty 410 earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Trimi and Fifty 410.

How they sit against everyone else